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加拿大采取新措施,确保未来COVID-19治疗手段及疫苗供应

2020-9-1 09:45|发布者: 热点新闻|查看: 117|评论: 0

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摘要:签约潜在疫苗扩大制药产能保障未来疫苗供应8月31日上午在蒙特利尔,我们宣布了正采取的新步骤,以确保我们可以使用潜在的COVID-19疫苗。因为随着越来越多的人返回工作岗位、而我们的孩子们将返回教室的时候,我们一 ... ...


签约潜在疫苗
扩大制药产能

保障未来疫苗供应

8月31日上午在蒙特利尔,我们宣布了正采取的新步骤,以确保我们可以使用潜在的COVID-19疫苗。因为随着越来越多的人返回工作岗位、而我们的孩子们将返回教室的时候,我们一如既往继续专注于确保所有加拿大人的安全和健康——不论您住在加国何处,做什么工作或者身为什么样的人。

正是基于这样的原因,我们签署了两项新协议:一份与Novavax,一份与Johnson&Johnson,以预留他们正在开发的数百万剂疫苗。由于这些协议以及我们先前与辉瑞和Moderna达成的协议,我们已保留了至少8800万剂潜在的疫苗,并留下选项可以获得数千万更多的疫苗。

另外,由于我们还需要在本土生产和分发最终的疫苗,我们投资扩大国家研究委员会(NRC)在蒙特利尔的厂房。到明年,皇家山(Royalmount)的生物制造工厂将能够每月生产多达200万剂的疫苗,以确保我们的安全。

要了解有关我们与研究人员和科学家们所进行的更多工作,以及有关我们为确保您的安全所采取的步骤的所有详细信息,请看以下新闻



mpvideo

video: https://mp.weixin.qq.com/mp/readtemplate?t=pages/video_player_tmpl&action=mpvideo&auto=0&vid=wxv_1499404483976577029




新闻通稿

加拿大采取新措施,确保未来COVID-19治疗手段及疫苗供应

New measures to ensure the supply of future vaccines and therapies against COVID-19 

2020年8月31日  魁北克蒙特利尔  总理办公室



加拿大战胜COVID-19的能力取决于有效且经过验证之疫苗的开发、生产和分销。因此,加拿大联邦政府与研究人员和科学家紧密合作,以更好地了解这种病毒并保护加拿大人的健康。

贾斯廷•特鲁多(Justin Trudeau)总理今天宣布,政府已经和强生公司(Johnson & Johnson)和诺瓦瓦克斯(Novavax)达成原则性协议,以购买数百万剂实验性COVID 19疫苗。这些协议是继辉瑞(Pfizer)和Moderna已经达成协议之后的进一步行动,这些协议是根据COVID-19疫苗工作组的建议而制定的。

有了这些新增的协议,加拿大现在已经稳固四个领先候选疫苗的使用权。政府将继续与多家领先的制药公司进行谈判并签署其他协议,以确保潜在疫苗在加拿大的供应。



总理还宣布拨款在蒙特利尔人类健康治疗研究中心(Human Health Therapeutics Research Centre in Montréal)建立新的生物制造设施。通过公私合作,新的生产设施将使加拿大国家研究委员会(NRC)的疫苗产能在明年提升到每月200万剂。这将有助于确保加拿大有能力为有需要的加拿大人生产足够剂量的疫苗,例如一线工作人员、长期护理工人以及如果感染COVID-19则会身患重病风险的人士。

加拿大联邦政府将继续探索并寻求所有有希望的可能选项,以确保潜在疫苗的供应、并更好地保护加拿大人民的健康和安全。



引述

加拿大总理贾斯廷•特鲁多(Justin Trudeau)阁下:

“在我们继续齐心协力、努力遏制COVID-19疫情大流行对加拿大人民的健康以及社会和经济之影响的同时,我们还必须最大程度地战胜这种病毒。为此,我们需要投资开发几种有前途的疫苗,并确保我们能够尽快将疫苗生产出来并分发给尽可能多的加拿大人。这就是我们向前迈进、走向全面复苏的可持续道路。”

创新、科学和工业部长贝恩斯(Navdeep Bains)阁下:

“我们政府致力于提供安全有效的COVID-19治疗手段和疫苗。因此,我们必须在加拿大增强我们的生物制造能力。今天宣布的这项新设施投资将帮助NRC提升潜在疫苗的生产能力到每月200万剂。此举还将帮助生产用于临床试验和重点人群的疫苗。”

卫生部长海度(Patty Hajdu)阁下:

“我们将继续确保加拿大政府尽一切努力为加拿大人民提供安全而有效的COVID-19疫苗。在我们为尽快保护加拿大人民免受免受COVID-19侵害的努力中,今天宣布的新措施标志着一个重要里程碑。”

公共服务及采购部长阿南德(Anita Anand)阁下:

“在我们继续采购抗击COVID-19疫情大流行所需物资和设备的同时,我们同样专注于规划未来,包括确保为加拿大人民提供潜在的疫苗。我们正在采取积极的措施来确保一些最有前途的候选疫苗,以确保一旦这些疫苗获得核准之后加拿大人可以尽快使用。”



事实简要


  • 加拿大联邦政府将在两年内投资1.26亿元建设新设施。然后,政府将每年提供2000万元用于设施的运营成本。

  • 人类健康治疗研究中心的NRC设施汇集了各类专家、设备和专业知识。从临床前发现到生物制造、确定特征、纯化以及技术转让材料的拟订等等,他们为治疗药物开发人员提供全方位的服务。

  • 加拿大政府现已与以下公司签署协议以获取疫苗:

  • 强生公司(Johnson & Johnson),将提供多达3800万剂的候选疫苗Ad26.COV2.S。

  • 诺瓦瓦克斯(Novavax),将提供多达7600万剂的候选疫苗NVX-CoV2373。

  • 辉瑞公司(Pfizer)将提供至少2000万剂基于mRNA的候选疫苗BNT162。政府正在与该公司进行谈判,让协议包括获得更多剂量的选项。

  • Moderna,将提供多达5600万剂的候选疫苗mRNA-1273。

  • 目前,尚无被批准用于预防COVID-19的疫苗。有多个疫苗正在临床试验中或正处于开发阶段。在完成更多研究之后,加拿大卫生部将审查每种疫苗的安全性、有效性和生产质量的证据,以确定是否会批准某种疫苗可以在加拿大使用,此后才能将此疫苗让加拿大人接种。

  • 2020年春季,加拿大联邦政府宣布了总计4,400万加元的资金,允许NRC提升其在人类健康治疗研究中心的设施。这项投资将确保该设施符合相关的良好生产规范,以有利于开发、测试、扩大规模和批量生产有希望的候选疫苗。此举还将使得该生产设施可以从2020年11月开始将初始产能提升至每月250,000剂疫苗。

  • 2020年4月23日,联邦政府宣布投资10亿加元用于《动员科学抗击COVID-19疫情计划》。这笔资金将用于开发疫苗和治疗手段,以及病毒追踪等。在这笔款项中,有6亿元将用于支持私营产业开发疫苗、进行临床治疗试验以及在加拿大寻求生物制造机会的工作。

  • 加拿大联邦政府还为加拿大疫苗生产的制造和包装等最后阶段提供所需的设备和用品。它还购买了安全、有效免疫所需的设备,包括注射器、针头和酒精拭子等。


相关链接

  • 投资实施新战略,支持COVID-19医疗研究与疫苗研发

  • 加拿大联邦政府宣布重大举措,通过疫苗及疗法来治疗并预防COVID-19疫情




英文原文



New measures to ensure the supply of future vaccines and therapies against COVID-19

August 31, 2020   Montréal, Quebec    Prime Minister’s Office

Canada’s ability to defeat COVID-19 depends on the development, production, and distribution of an effective and proven vaccine. That is why the Government of Canada is working closely with researchers and scientists to better understand the virus and protect the health of Canadians.

The Prime Minister, Justin Trudeau, today announced that agreements in principle have been reached with Johnson & Johnson and Novavax to procure millions of doses of experimental COVID 19 vaccines. These agreements add to those already reached with Pfizer and Moderna, which were made following the recommendations of the COVID-19 Vaccine Task Force.

With these additional agreements in place, Canada has now secured access to four of the leading vaccine candidates. The government will continue to negotiate and sign other agreements with a number of leading pharmaceutical companies, to ensure the supply of potential vaccines in Canada.

The Prime Minister also announced funding to establish a new biomanufacturing facility at the Human Health Therapeutics Research Centre in Montréal. Through a public-private partnership, the new building will enable the National Research Council of Canada (NRC) to increase vaccine manufacturing to up to two million doses per month by next year. This will help ensure our country’s ability to produce enough doses of the vaccine for Canadians who need them, such as front line workers, long-term care workers, and those at risk of becoming seriously ill if they contract COVID-19.

The Government of Canada will continue to explore and pursue all promising options to ensure the supply of potential vaccines and better protect the health and safety of Canadians.

Quotes

“As we continue to work together to limit the impact of the COVID-19 pandemic on the health of Canadians, as well as its social and economic effects, we must also maximize our chances of defeating the virus. To do this, we need to invest in the development of several promising vaccines and ensure that we can manufacture and distribute the vaccine to as many Canadians as possible, as quickly as possible. That is how we will move forward on a sustainable path to a full recovery.”

—The Rt. Hon. Justin Trudeau, Prime Minister of Canada

“Our government is committed to delivering safe and effective treatments and vaccines against COVID-19. We must therefore grow our biomanufacturing capacity here in Canada. The funding announced today for this new facility will help the NRC increase production of potential vaccine doses to up to two million per month. It will also help manufacture vaccines for clinical trials and priority populations.”

—The Hon. Navdeep Bains, Minister of Innovation, Science and Industry

“We will continue to ensure that the Government of Canada is doing everything possible to make a safe and effective COVID-19 vaccine available to Canadians. Today’s announcement marks an important milestone in our efforts to protect Canadians from COVID-19 as soon as possible.”

—The Hon. Patty Hajdu, Minister of Health

“As we continue our work to purchase the supplies and equipment that are necessary to combat the COVID-19 pandemic, we remain equally focused on planning for the future, including securing potential vaccines for Canadians. We are taking an aggressive approach in procuring a portfolio of the most promising vaccine candidates in order to ensure that Canadians will have access to them as quickly as possible once they have been approved.”

—The Hon. Anita Anand, Minister of Public Services and Procurement

Quick Facts

  • The Government of Canada will invest $126 million over two years to build the new facility. The government will then provide $20 million per year to cover operating costs.

  • The NRC facilities at the Human Health Therapeutics Research Centre bring together a variety of specialists, equipment, and expertise. They provide a full range of services to therapeutics developers, from preclinical discovery to biomanufacturing, characterization, purification, and the creation of materials for technology transfer.

  • The Government of Canada has now signed agreements with the following companies to obtain vaccines:

  • Johnson & Johnson, which will supply up to 38 million doses of its vaccine candidate Ad26.COV2.S.

  • Novavax, which will supply up to 76 million doses of its vaccine candidate NVX-CoV2373.

  • Pfizer, which will supply a minimum of 20 million doses of its mRNA-based vaccine candidate, BNT162. The government is negotiating with the company to have the agreement include options for obtaining additional doses.

  • Moderna, which will supply up to 56 million doses of its vaccine candidate mRNA-1273.

  • Currently, no vaccines have been approved to prevent COVID-19. Many vaccines are in clinical trials or under development. When additional studies have been completed, Health Canada will review the evidence of safety, efficacy, and manufacturing quality for each vaccine to determine whether individual vaccines will be approved for use in Canada, before they are used to vaccinate Canadians.

  • In the spring of 2020, the Government of Canada announced a total of $44 million in funding to allow the NRC to upgrade its facilities at the Human Health Therapeutics Research Centre. This investment will ensure that the facility complies with good manufacturing practices related to the development, testing, and scale-up and production of promising vaccine candidates. It will also enable the preliminary production of 250,000 doses of vaccine per month starting in November 2020.

  • On April 23, 2020, the Government of Canada announced an investment of more than $1 billion through the Plan to Mobilize Science to fight COVID-19. This funding will be used to develop a vaccine and treatments, as well as to track the virus. Of this amount, $600 million will support private sector work to develop a vaccine, conduct therapeutic clinical trials, and pursue biomanufacturing opportunities in Canada.

  • The Government of Canada is also securing the equipment and supplies needed for the final phases of manufacturing and packaging for vaccine production in Canada. It is also purchasing the equipment required for safe and effective immunization, including syringes, needles, and alcohol swabs.


Associated links

• Coronavirus disease (COVID-19)

• COVID-19 Vaccine Task Force

• COVID-19 Therapeutics Task Force

• Prime Minister announces new support for COVID-19 medical research and vaccine development

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