摘要:如果您在今日的职位更新中没有找到适合自己的职位，可以浏览该公众号近日的招聘信息。通常情况下，近一个月的职位都会有效。PhD position in genome stability and Cancer –Sept 2022All organisms can suffer DNA ... ...
PhD position in genome stability and Cancer –Sept 2022
All organisms can suffer DNA double-strand breaks (DSBs), during meiosis, during DNA replication as elongating forks stall or collapse, or as a consequence of treatment with DNA damaging agents such as ionizing radiation. If left unrepaired, the consequences for genomic stability would be disastrous, resulting in chromosomal deletions and translocations leading to apoptosis or carcinogenesis. It is becoming increasingly clear that tumour formation can be triggered by mutations in genes involved in the surveillance of the genome integrity such as PALB2 and BRCA2. Defects in these genes can be exploited through synthetic lethal approaches, such as the inhibition of Poly(ADP)ribose polymerase. The laboratory studies mainly the repair of DNA double-strand breaks at the biochemical, cellular and genetic level. We have openings for students to study the roles of regulators of DNA double-strand break repair and the use of novel therapeutic compounds targeting cancer cells. Our research is at the interface of breast/ovarian cancer but also , but also of genome engineering with the CRISPR/Cas system.
For more information about our research programs, please visit: jeanyvesmasson.com and the following references: Nature Structural and Molecular Biology 17:1247-54 ; Cell Reports 6, 553-564; Nature Cell Biology 17, 1446-57, Molecular Cell 61 :405-18; Nucleic Acids Research 47:10662-10677; Nature Communications 10: 2954; Trends Biochem Sciences 45: 779-793.
The chosen candidate will be primarily located at the Laval University Cancer Research Center in old Quebec city in Canada. This is a very safe place to live in. Moreover, the student fees of foreign Laval University PhD students are the same as Canadian students.
Applicants should have a BSc or MSc degree in relevant fields of biochemistry or molecular biology or a related field. Applicants should be highly motivated for basic biomedical research and have excellent communication skills in English. Applicants with bioinformatics experience are also welcomed to apply. Interested applicants should send a curriculum vitae including previous publications and two references to:
Laval University Cancer Research Center 9 McMahon, Québec (Qc) G1R 2J6
Funding category: Contrat doctoral
IRSC
PHD title: Doctorat en biologie Cellulaire et Moléculaire
PHD Country: Canada
MSc, PhD and postdoctoral positions are available for talented and highly motivated individuals that are interested in investigating DNA double-strand break repair and human diseases such as cancer or Fanconi anemia.
Please send your application including a CV and short letter describing your motivation and goals for joining the lab in the current form below. One excellent first author publication is required for applying for a postdoctoral position.
Please don't hesitate to contact any current members (or past members) for feedback on the lab.
Update - I have an opening for a funded graduate student position (in winter 2023). There is no space in the lab for 2021 due to COVID-19 and we are moving in a new cancer institute in Quebec City in Sept 2022.
CONTACT INFORMATION
Centre de Recherche du CHU de Québec (Axe Oncologie)
